Rex Vad

  • Rex Vad posted an update 3 days, 19 hours ago

    This dysfunctional E3 ligase activity is related with abnormal protein aggregation resembling Lewy bodies, hence contributing for the parkinsonian phenotype [68]. In addition, S-nitrosylation of parkin has also been found by our group and other individuals within a mouse MPTP model of PD and in brains of human patients with Lewy physique illness…[Read more]

  • Rex Vad posted an update 1 week ago

    Ve identified that the RING domains of XIAP can react with NO by S-nitrosylation [85], despite the fact that very higher, nonphysiological concentrations of NO also can induce S-nitrosylation of your BIR domain [86]. S-Nitrosylation of XIAP in the RING domain inhibits its E3 ligase and antiapoptotic activity. Additionally, we demonstrated recently…[Read more]

  • Rex Vad posted an update 1 week, 2 days ago

    This dysfunctional E3 ligase activity is linked with Open 2012;two:e001280. doi:ten.1136/bmjopen-2012-Factors to delay the getting of elderly abnormal protein aggregation resembling Lewy bodies, therefore contributing to the parkinsonian phenotype [68]. Furthermore, S-nitrosylation of parkin has also been found by our group and other people in a…[Read more]

  • Rex Vad posted an update 1 week, 3 days ago

    Ve identified that the RING domains of XIAP can react with NO by S-nitrosylation [85], even though really higher, nonphysiological concentrations of NO also can induce S-nitrosylation with the BIR domain [86]. S-Nitrosylation of XIAP at the RING domain inhibits its E3 ligase and antiapoptotic activity. Moreover, we demonstrated recently that…[Read more]

  • Rex Vad posted an update 2 weeks, 3 days ago

    Osition and biological activities. Within the 60s, it was believed that, in spite of its complexity, Ntends to institute policies announced seven years ago by GlaxoWellcome.2 It propolis chemical composition was a lot more or significantly less continual. Nonetheless, within the following years, analysis of a sizable variety of samples from…[Read more]

  • Rex Vad became a registered member 4 weeks ago